Home Health LDN and the Immune System

LDN and the Immune System

The immune system is a complex network involving cells, organs, proteins, tissues, and biological processes. A healthy, functioning immune system is vital to your health and wellness. It keeps us healthy by detecting and responding to viruses, disease-causing organisms, cancer cells, and bacteria. With the looming threat of the novel coronavirus COVID-19, as well as the flu and common cold, a strong immune system is vital. Its hypothesized that due to its mechanism of action LDN can modulate an immune response and has many Americans looking into where they can buy LDN for the immune system.

If you are looking to buy LDN for the positive effects on the immune system, you are not alone. This longevity therapy, known for its long list of benefits, has a remarkable effect on the body due to its ability to increase endogenous opioids such as Met-enkephalin and reduce chronic inflammation.

What is LDN?

Low Dose Naltrexone (LDN) is a drug that has been used for over 40 years. It is approved by the FDA and in clinical practice was shown to be an effective treatment for many inflammation related diseases. Naltrexone at high doses is used to control cravings for opioids and alcohol, where lower doses are helpful for multiple autoimmune conditions which are probably tied to chronic inflammation: fatigue, chronic pain, and MS. LDN is an effective therapy that can also increase endorphin levels, improve mood, reduce food cravings, and modulate the immune system.

LDN and Met-enkephalin

Chemicals and opioids are released into our bodies for a number of reasons. Chemical releases are often in response to a form of stimuli such as pain or pleasure. Met-enkephalin is an opioid found in the adrenal gland. It can stimulate an immune response and trigger different immune cells.  Research has shown that by increasing Met-enkephalin, immune cells like T-cells, NK cells, and IL-2, TH-2 increase, and in turn, diseases like AIDS, opportunistic diseases, and certain types of cancer decrease. To put it simply, lower Met-enkephalin levels result in a weakened immune system.

Research has looked at the effect of Met-enkephalins on immune cells. In 2014 a study was conducted, looking at 50 patients with cancer. Many cancer treatments, specifically chemotherapy and radiotherapy, are known to damage the immune system. This study found that the immune system was boosted with an increase in Met-enkephalin. It concluded that it is a strong immune system booster with significant potential to restore immune system damage caused by chemotherapy and would be a beneficial chemotherapy additive.

What does this have to do with LDN?

LDN can increases Met-enkephalin levels, causing this positive chain-reaction of an improved immune system and reduced risk of disease. LDN works by temporarily blocking opioid receptors, stimulating endorphin release, reducing inflammation, and modulating the immune system. A 2017 study found that Met-enkephalin levels were lower in those with multiple sclerosis and that LDN was able to increase and restore these levels.

LDN and Inflammation

Inflammation is the root cause of many diseases and illnesses and can reduce the effectiveness of one’s immune system. With age, there is an increased risk for chronic inflammation and weakening of the immune system. By reducing inflammation, the immune system can be strengthened. LDN is able to reduce pro-inflammatory cytokines, which reduces inflammation.

A 2017 study published in Biomedicines looked at the immune effects of LDN on women with fibromyalgia with an average age of 46 years. These women took LDN for 8 weeks. After the 8-weeks, the study found a reduction in inflammation and an 18% reduction in symptoms. The research suggested that it was an effective treatment as it reduced several pro-inflammatory cytokines, ultimately reducing inflammation.


With a long list of health benefits, LDN is becoming more widely used. It may be prescribed to treat fibromyalgia, Crohn’s and ulcerative colitis, multiple sclerosis, fertility issues, and weight loss. The most common dosage for LDN is 4.5 mg daily. Optimal dosing can vary with each person and is important for maximizing the benefits of the drug. When you buy LDN, your provider will work with you to help determine the right dosage. If your dose is too low, you will not see the benefits you could be experiencing if it were higher. If it is too high, you may experience an increase in side effects like insomnia and headaches.

A clinic familiar with LDN is able to take a strategic trial and error approach. For example, patients who buy low dose naltrexone online from AgelessRx start with 1.5mg capsules daily. This is increased by 1.5mg every ten to fourteen days until 4.5mg is reached. Patients will then stay at this dosage for about two to three months to determine if they are achieving the desired benefits. Following that, their dedicated medical team will work with the patient to adjust the dosage, if needed.

LDN dosage can be increased to up to 9mg a day.

LDN is typically taken before bed due to the morning activity of the endorphin system. Although capsules are the most common form of LDN, there are alternatives. Tablets, sublingual’s and liquid can be used if the patient has difficulty digesting capsules.

Immunocompromised individuals include those who have cancer, diabetes, obesity, heart conditions, and more. These individuals are at severe risk for COVID-19 as well as other viruses. Vulnerable populations are told to take additional precautions to protect themselves.

Those with a compromised immune system, along with the general public, are looking for ways to strengthen their immune system. Consequently, more people are discovering the incredible effects of Low Dose Naltrexone and opting to buy LDN to boost their immune system.


Most Popular

This Is What’s Happening To Your Brain During Your Period, From A Neuroscientist

Headaches during your period may be due to the fluctuation in hormone levels, low...

You Need To Know About Double-Masking

What’s better than a facial mask? Two facial masks! We all know that masking delivers a shot of nutrition as well as a ton...

The Most Versatile Barbells for Home Workouts

One of the most effective ways to work your full body from home is with a barbell. This powerhouse piece of equipment serves novices...

This Trick For Creamy Vegan Pasta Uses A Secret Protein-Packed Ingredient

The idea for this dish is based on advice we first got from culinary...

Recent Comments